Yep, that's Mickey Rourke in Iron Man 2, via USA Today and AICN. Apparently, Rourke is playing Whiplash, a supervillain I've never heard of (but as far as I can tell, he's more or less the crappiest bad guy ever).
Man, the more I look at that picture, the more certain I am that this has gotta be a joke. (A) The dude's clearly crashing some sort of NASCAR event—which seems like something Mickey Rourke does all the goddamn time, but probably not something a supervillain would do. (B) I think he might be wearing a dress. (C) Unless there's a scene in which Mickey Rourke and Robert Downey Jr. call each other the night before their big fight and plan to go twinsies, I'm not feelin' any film that features not one but two super-dorky goatees. (D) I guess this is neither here nor there, but when did Mickey Rourke start looking like the bad guy from Big Trouble in Little China?