Another good one is Guardian Games. A game store that sells table top role playing games, board games of all kinds & collectible card games. The place is huge, with lots of tables open for gaming.

In the back they have their bar, The Critical Sip, where there are also more open tables. So one can game and drink. Once a month they have a board game night where you can stop in for pizza, beer and to try out board games.

http://www.ggportland.com/

345 SE Taylor Street
Portland, OR 97214