"In the NRC 2006 report, Fluoride in Drinking Water: A Scientific Review of EPA's Standards, the National Research Council (NRC) reported that "several lines of information indicate an effect of fluoride on thyroid function."
Specifically, the report discussed research showing that:
"fluoride exposure in humans is associated with elevated TSH concentrations, increased goiter prevalence, and altered T4 and T3 concentrations" with "similar effects on T4 and T3…reported in experimental animals."
In addition, the NRC discussed research linking fluoride to impacts on parathyroid activity, impairment of glucose tolerance, and possibly the timing of sexual maturity.
In light of these findings, the NRC panel recommended that the "effects of fluoride on various aspects of endocrine function should be examined further, particularly with respect to a possible role in the development of several diseases or mental states in the United States"
(1.). Despite this, proponents of fluoridation continue to ignore the scientific literature concerning the detrimental effects that fluoride has on the endocrine system." - Mary Shomon, The Daily Activity Every Middle Aged Woman Should Beware of (Aug, 2011).
As far as the cancer risk goes: http://youtu.be/ClqK7XvfLg0 .
Heart risk research from 2012: http://journals.lww.com/nuclearmedicinecom…
Akiniwa, Kenji, Re-Examination of acute toxicity of fluoride, Fluoride, 1997, 30:2, 89-104
"The acute toxic dose of fluoride has been believed to be 2 to 5 mg or 8 mg/kg of body weight. However, acute fluoride poisonings have occurred at doses of 0.1 to 0.8 mgF/kg of body weight in the USA. In Japan, a school-based anticariogenic program is being carried out with fluoride mouth rinses containing 500 to 2000 ppm sodium fluoride on approximately 158,000 persons, consisting mainly of elementary and junior high school children. Thus the safety problem of this treatment attracts much attention. Fluoride retention is said to be around 15 to 30% in fluoride mouth rinsing. In this paper, on the basis of toxic doses estimated in outbreaks of fluoride poisoning, the potential for acute poisoning by fluoride ingested during mouth rinsing is assessed. Acute fluoride poisoning is shown to be caused by exposure to lower doses of fluoride than commonly suggested. The toxic dose of fluoride should therefore be re-examined."
1. National Research Council. 2006. Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press: Washington, DC.
2.Toxicol Ind Health. 2009 Feb;25(1):49-57. doi: 10.1177/0748233709102720.
Fluoride-induced thyroid dysfunction in rats: roles of dietary protein and calcium level.
Wang H, Yang Z, Zhou B, Gao H, Yan X, Wang J.
Shanxi Key Laboratory of Ecological Animal Science and Environmental Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, People's Republic of China.
3.Nuclear Medicine Communications:
January 2012 - Volume 33 - Issue 1 - p 14–20
Association of vascular fluoride uptake with vascular calcification and coronary artery disease
Li, Yuxina; Berenji, Gholam R.a; Shaba, Wisam F.a; Tafti, Bashira; Yevdayev, Ellaa; Dadparvar, Siminb
4. Mary Shomon's quoted text, http://articles.mercola.com/sites/articles…
5. Akiniwa, Kenji, Re-Examination of acute toxicity of fluoride, Fluoride, 1997, 30:2, 89-104
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