Thanks to cagey advertising, audiences will be in for a surprise as Side Effects unfolds: What starts as an intensely accurate study of a young woman's depression gradually contorts itself into something else entirely. Steven Soderbergh's calculated eye, paired with Scott Z. Burns' script, finds plenty to grab onto in the story of 28-year-old graphic designer Emily (Rooney Mara), who struggles with crippling depression. After a jarring suicide attempt, Dr. Jonathan Banks (Jude Law) starts Emily on Ablixa, a new, unproven antidepressant, at which point things get even more intense. by Erik Henriksen