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COURTESY OF ANDIE MAIN

Andie Main is a Portland comedy scene institution. But after seven years as a regular fixture—she founded the monthly Revolution Comedy and summertime Cool Kids Patio Show, and achieved a dream of being a regular host at Helium—the time has come for Main to seek her fortune in another city. Talking with Main is a laugh riot and she cracked us both up, multiple times, during what was supposed to be an earnest conversation about growing up in Portland, the perils of dating after divorce, and the way social justice work made Main feel like a target.

Suzette Smith is the arts & culture editor of the Portland Mercury. Go ahead and tell her about all your food, art, and culture gripes: suzette@portlandmercury.com. Follow her on Twitter, Bluesky,...